Power is the ability to do work, and work is the transfer of power from one way to another.
Cirro energy reviews
The aim of the Danish Center for Interventional Research in Radiation Oncology (CIRRO) is to establish individualized radiotherapy, which will lead to improved tumours control with fewer side effects for a large proportion of cancer patients. This project encompasses biological, clinical, and technical studies, which will form the basis for clinical implementation of biology-guided adaptive radiotherapy. A structure for interaction between the involved institutions, activities, and applications has been developed. In collaboration with all Danish radiotherapy departments, we have established work packages WP for translational research, and intervention protocols. The clinical implementation of the various new methods in radiotherapy is being evaluated.Cirro Energy Reviews are currently involved in 25 clinical intervention protocols, with a total of 1182 patients included so far in Denmark. By May 2011, a total of 149 scientific papers have been published or accepted in peer-reviewed international journals. Appendix 1 and an additional 24 documents are under review appendix 2. CIRRO has been involved in the organization of three international meetings and two PhD courses in radiotherapy. More than 300 presentations, oral and posters have been presented at international conferences.
Interventional research
The aim of the Danish Center for Interventional Research in Radiation Oncology (CIRRO) is to establish individualized radiotherapy, which will lead to better tumours control with fewer side effects for a large proportion of cancer patients. This project encompasses biological, clinical, and technical studies, which will form the basis for clinical implementation of biology-guided adaptive radiotherapy.
Structure and organization
The organizational structure presented in the original application has been implemented, with the formation of WPs, IPs, and a Project Coordinating Committee (PCC). An academic coordinator appointed in March 2009. The administrative coordination has been strengthened by including CIRRO responsible contact persons from the participating centers. It reflected the need for a smooth connection to the centers daily, which was impossible with the much larger PCC. The PCC has met so far three times and will continue to meet once a year.
The main conclusions from the meeting were:
- CIRRO is a unique national research center engaging all radiotherapy departments in Denmark
- Research in work packages is progressing well and according to plan with very carefully thought out ideas and realistic work programs
- Most of the described clinical trials have been activated, and a few more lawsuits have been added
- The translational research is of very high quality and several translational research activities have been added to the ongoing clinical projects
- The CIRRO project brings Denmark in an internationally very competitive position in new developments in cancer research. The advisory committee had three main pieces of advice for future events.
- CIRRO should enhance the incorporation of energetic translational activities e.g., functional imaging, genetic analyses, and use of fiducial markers into existing clinical trials and new clinical projects.
- CIRRO should work on strategies for exchanging young investigators between laboratories worldwide, and 3) the national central dose plan bank (WP09) is unique. It should be extended beyond the quality assurance of CIRRO trials.